The MISRA Safety Case working group has published the first two of a series of white papers on the public road transport system, motivated by the ambitions of government and the automotive industry to deploy self-driving vehicles on the public roads. These white papers take a step back from the minutiae of technology and standards to consider the bigger picture of safety on the public roads. The starting point is a consideration of the historic situation and what is effectively the undocumented safety argument. The work builds high-level models that highlight the relationships between the many different aspects relevant to the prevention of harm to humans using the public road network and forms the context for a vehicle safety argument. Some of these aspects may have assumptions explicitly documented about them while other may have been ignored or overlooked to the detriment of the argument. In the SSS’25 talk we will provide an overview of these papers and in particular highlight the effect of the introduction of autonomous road vehicles on the implicit high-level road safety argument and the way this affects the safety argument for a vehicle. These white papers can be downloaded from the Publications area at https://misra.org.uk/publications