How do you manage change in a world of rapidly changing technology and ever-changing priorities? This paper discusses the roles of Management of Change (MoC) and Change Management (CM) in the context of systems being designed, built, and operated today. This is of particular concern where there are safety, security, or environmental issues. It is not that significant technological changes have not happened in previous decades, they have, but the nature, functionality and complexity of today’s systems place a particular onus on traceability, auditability, and assurance, to ensure that these systems are safe and fit for purpose both for today’s operating environments and for those of the future. MoC enables intelligent business decisions at every stage of the project, system, and safety lifecycles. Acknowledgement and integration of CM within companies, engineering teams, and projects is increasingly important for high-quality outputs and outcomes.